Asian Journal of Analytical Chemistry

The detection of ascorbic acid in orange (Rutaceae Sp.) using titration technique

2023-05-27T15:54:57+07:00

Vitamin C is a vitamin that belongs to the group of water-soluble vitamins. Some sources of vitamin C are obtained from fresh vegetables and fruits. Vitamin C has several functions in the body, including helping to replenish the body's supply of twins and optimizing functionality. This study aims to determine the levels of vitamin C in lime, kaffir lime, tangerine, and lemon by the iodometric titration method. The sample used in this study was obtained from the Brosot market, Kec. Galur, Kab. Kulon Progo, Yogyakarta. The vitamin C levels obtained from lime, kaffir lime, tangerine, and lemon were 0.004%, 0.004%, 0.002%, and 0.005%.

Identification of antibiotic by chromatographic and spectrophotometric methods – A Review

2023-05-28T10:02:34+07:00

The purpose of this article to review the validation and content of antibiotics using various chromatographic and spectrophotometric methods. This review article used five analytical methods on antibiotics, namely high-performance liquid chromatography (HPLC), Fourier transform infrared (FTIR), gas chromatography (GC), ultraviolet-visible (UV-Vis) spectrophotometer and liquid chromatography/mass spectrophotometer (LC/MS) methods. Antibiotics are the most widely used drugs for infections caused by bacteria. Based on a review of several studies related to antibiotic analysis, the general techniques applied are HPLC, FTIR, GC, UV-Vis Spectrophotometry, and LC-MS. Analysis of this antibiotic is a massive challenge due to its sensitivity and instability to various conditions.

The determination of vitamin C in guava (Myrtaceae species) using spectrophotometric approach

2023-05-28T09:36:07+07:00

Vitamin C is one of the essential vitamins for body health. However, vitamin C cannot be produced by the body itself. Thus, to fulfill the vitamin C requirement, it can be obtained by consuming fruits and vegetables. The purpose of this study was to find out and analyze the levels of vitamin C in guava (Psidium guajava L.), crystal guava (Psidium guajava (L.) Merr.), and water guava (Syzygium aquenum). This study used UV-Vis spectrophotometry to analyze the vitamin C content. The results of vitamin C levels in samples such as red guava, crystal guava, and water guava were 21.16 mg/5 g ± 0.005, 20.79 mg/5 g ± 0.029, and 19.16 mg/5 g ± 0.089, respectively. Based on these outcomes, it can be concluded that high levels of vitamin C can be acquired in red guava (Psidium guajava L.)

Analysis of antacid tablets using the alkalimetric titration method

2023-06-07T14:41:58+07:00

Titrimetry is a quantitative analysis concerned with measuring the volume of a solution of known concentration required to react with the substance to be determined. On the other hand, alkalimetry determines the levels of acidic compounds that are reacted with essential standard solutions. Antacids can treat stomach disorders resulting from excess stomach acid production. The active ingredient is a mixture of magnesium hydroxide and aluminum hydroxide which is a weak base that reacts with acids. This study aims to determine whether the levels of antacid tablets in several pharmacies in Bandar Lampung City by looking at the expiration date meet USP30_NF25 requirements, namely between 90.0% -110% of the amount stated on the label. The method used is alkalimetry with a back titration technique, in which excess acid is added to the sample to react with antacids, and the excess acid is titrated using sodium hydroxide with phenolphthalein solution as an indicator.

NSAID Analysis Using Chromatographic and Spectrophotometric Methods

2023-05-28T09:40:10+07:00

The purpose of this review article to evaluate the content of Nonsteroidal anti-inflammatory drugs (NSAID) using chromatographic and spectrophotometric methods. This journal review uses seven analytical methods on NSAID , namely high performance liquid chromatography (HPLC), fourier transform infrared (FTIR), gas chromatography (GC), thin layer chromatography (TLC), and spectrophotometry methods. The outcomes of every method have been elaborated in this paper and all of them can be used to detect the NSAID compounds.